BDBM457217 US10738056, Compound A1085::US10738056, Compound A1089

SMILES COC1CCCCC1NC(=O)c1c(C)[nH]c2c(c(nn2c1=O)C(F)(F)F)-c1ccccc1

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457217   

TargetCyclic GMP-AMP synthase [155-522](Homo sapiens (Human))
Aduro Biotech

US Patent
LigandPNGBDBM457217(US10738056, Compound A1085 | US10738056, Compound ...)
Affinity DataIC50: <20nMAssay Description:Protein was expressed and purified from E. coli BL21 DE3 Rosetta 2 (EMD Millipore) cells using standard techniques. Cells were grown in 2x yeast extr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclic GMP-AMP synthase [155-522](Homo sapiens (Human))
Aduro Biotech

US Patent
LigandPNGBDBM457217(US10738056, Compound A1085 | US10738056, Compound ...)
Affinity DataIC50:  135nMAssay Description:Protein was expressed and purified from E. coli BL21 DE3 Rosetta 2 (EMD Millipore) cells using standard techniques. Cells were grown in 2x yeast extr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent