BDBM457787 US10738074, Example 18
SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=S)O[C@H]3[C@@H](O[C@H](COP(O)(=S)O[C@@H]1[C@@H]2F)[C@H]3N=[N+]=[N-])n1cnc2c(N)ncnc12
InChI Key
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 457787
TargetStimulator of interferon genes protein [H232R](Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: 0.400nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
TargetStimulator of interferon genes protein [1-379,R71H,G230A,H232R,R293Q](Human)
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair