BDBM457789 US10738074, Example 19

SMILES Nc1nc2n(cnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(O)(=S)O[C@H]3[C@H](O[C@H](COP(O)(=S)O[C@@H]1[C@@H]2F)[C@H]3N=[N+]=[N-])n1cnc2c(N)ncnc12

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 457789   

TargetStimulator of interferon genes protein [H232R](Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM457789(US10738074, Example 19)
Affinity DataEC50:  1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM457789(US10738074, Example 19)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent