BDBM457804 3,3'-[(1S,6R,8R,9S,14R,16R,17R,18R)-17,18- difluoro-3,11-dioxido-3,11-disulfanyl- 2,4,7,10,12,15-hexaoxa-3,11- diphosphatricyclo[12.2.1.16,9]octadecane-8,16- diyl]bis(5-amino-3,6-dihydro-7H- [1,2,3]triazolo[4,5-d]pyrimidin-7-one)::US10738074, Example 31

SMILES Nc1nc2n(nnc2c(=O)[nH]1)[C@@H]1O[C@@H]2COP(S)(=O)O[C@@H]3[C@H](F)[C@@H](COP(S)(=O)O[C@@H]1[C@@H]2F)O[C@H]3n1nnc2c1nc(N)[nH]c2=O

InChI Key

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 457804   

TargetStimulator of interferon genes protein [H232R](Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM457804(3,3'-[(1S,6R,8R,9S,14R,16R,17R,18R)-17,18- difluor...)
Affinity DataEC50: <1nMAssay Description:16 nM of [3H] c-GAMP ligand was prepared by diluting into assay buffer, and 50 uL of this working stock was manually added to each well of the assay ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent