BDBM458180 US10752615, Compound 73

SMILES OCc1ccc2nc(NC(=O)c3ccc(s3)-c3cnco3)n([C@H]3C[C@]4(C3)CCN(C4)C(=O)C=C)c2c1

InChI Key InChIKey=DFNGRDVXGRSFSL-PJCCXEONSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458180   

TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
Gb005

US Patent
LigandPNGBDBM458180(US10752615, Compound 73)
Affinity DataIC50:  0.260nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Gb005

US Patent
LigandPNGBDBM458180(US10752615, Compound 73)
Affinity DataIC50:  1.02nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent