BDBM458337 4-(((1R,5S,8r)-3-benzyl-3-azabicyclo[3.2.1]octan-8-yl)(methyl)amino)-N-(6-fluoropyridin-2-yl)-5-methylthiophene-2-sulfonamide trifluoroacetic acid salt::US10752623, Example 57
SMILES CN([C@@H]1[C@H]2CC[C@@H]1CN(Cc1ccccc1)C2)c1cc(sc1C)S(=O)(=O)Nc1cccc(F)n1
InChI Key InChIKey=AHHQUAACMJYNLL-FZWXVRBQSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 458337
TargetSodium channel protein type 8 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 29nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 1 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 2.55E+3nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Xenon Pharmaceuticals
US Patent
Xenon Pharmaceuticals
US Patent
Affinity DataIC50: 5.85E+3nMAssay Description:This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...More data for this Ligand-Target Pair