BDBM458740 US10758539, Compound 4::US11369611, Compound 4

SMILES COc1cc2c(Oc3ccc4[nH]c(C)cc4c3F)ncnc2cc1OCCCN1CCC2(COC2)CC1

InChI Key InChIKey=BONKZDDXVSVZED-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458740   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kala Pharmaceuticals

US Patent
LigandPNGBDBM458740(US10758539, Compound 4 | US11369611, Compound 4)
Affinity DataKd:  330nMAssay Description:A VEGFR2 tagged T7 phage strain was prepared in an Escherichia coli (E. coli) derived from the BL21 strain. The E. coli were grown to log-phase, infe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kala Pharmaceuticals

US Patent
LigandPNGBDBM458740(US10758539, Compound 4 | US11369611, Compound 4)
Affinity DataKd:  330nMAssay Description:A competition binding assay was used to measure the ability of a compound to compete for binding of an immobilized adenosine triphosphosphate (ATP) s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent