BDBM458747 US10758539, Compound 18::US11369611, Compound 18

SMILES COc1cc2ncnc(Oc3ccc4n(C(=O)Nc5ccc(cc5)C(F)(F)F)c(C)cc4c3F)c2cc1OC

InChI Key InChIKey=QYWZSOCGTIQKSS-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458747   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kala Pharmaceuticals

US Patent
LigandPNGBDBM458747(US10758539, Compound 18 | US11369611, Compound 18)
Affinity DataKd: >1.00E+6nMAssay Description:A VEGFR2 tagged T7 phage strain was prepared in an Escherichia coli (E. coli) derived from the BL21 strain. The E. coli were grown to log-phase, infe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Kala Pharmaceuticals

US Patent
LigandPNGBDBM458747(US10758539, Compound 18 | US11369611, Compound 18)
Affinity DataKd: >1.00E+6nMAssay Description:A competition binding assay was used to measure the ability of a compound to compete for binding of an immobilized adenosine triphosphosphate (ATP) s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent