BDBM458782 US10759766, Compound C145
SMILES Fc1cc(NC(=O)c2cccc(c2)C(F)(F)F)cc(C(=O)c2ccc3ncc(nc3c2)N2CCOCC2)c1F
InChI Key InChIKey=CXWJKNYPVSWOKG-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 458782
Affinity DataIC50: <100nMAssay Description:KDR (VEGFR2): Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z′-LYTEŽ Method as described above...More data for this Ligand-Target Pair
Affinity DataIC50: <100nMAssay Description:BRAF and BRAF V600E: Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′...More data for this Ligand-Target Pair