BDBM458830 US10759792, Compound 9k::US11325908, Compound 9k

SMILES C1CN(CCN1)c1ncc(s1)-c1ccnc2[nH]c3ccccc3c12

InChI Key InChIKey=JJSHHNDZECULJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458830   

TargetCalcium/calmodulin-dependent protein kinase type II subunit gamma(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM458830(US10759792, Compound 9k | US11325908, Compound 9k)
Affinity DataIC50:  5.50E+4nMAssay Description:The inhibition of CaMKII activity was evaluated using a coupled assay measuring ADP released following ATP hydrolysis and phosphor-transfer to the pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCalcium/calmodulin-dependent protein kinase type II subunit delta(Homo sapiens (Human))
The Johns Hopkins University

US Patent
LigandPNGBDBM458830(US10759792, Compound 9k | US11325908, Compound 9k)
Affinity DataIC50: >1.00E+3nMAssay Description:Compounds were added in 5 uL volume to wells in UV transparent 96-well plates (½ area well size). The final compound concentrations tested ranged fro...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent