BDBM458854 US10759793, Example 7
SMILES OC[C@@H](O)COc1nc(nc(N[C@H]2CC[C@H](CC#N)CC2)c1F)-c1cnn2ccccc12
InChI Key InChIKey=NRQQXDCKITUCNW-BZUAXINKSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 458854
Affinity DataIC50: 2nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:The catalytic domains of human JAK1 (aa 850-1154), JAK2 (aa 826-1132), JAK3 (aa 795-1124) and Tyk2 (aa 871-1187) were expressed as N-terminal GST-fus...More data for this Ligand-Target Pair