BDBM459036 US10759794, Example 74

SMILES COc1ccc(C)c(n1)C(=O)N1CCN(Cc2c(nc3ccccn23)-c2ccc(Br)cc2)CC1

InChI Key InChIKey=VTOOBSYEGXFOPO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 459036   

TargetPotassium channel subfamily K member 9(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM459036(US10759794, Example 74)
Affinity DataIC50:  9.10nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPotassium channel subfamily K member 3(Homo sapiens (Human))
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM459036(US10759794, Example 74)
Affinity DataIC50:  67nMAssay Description:The investigations on the inhibition of the recombinant TASK-1 and TASK-3 channels were carried out using stably transfected CHO cells. Here, the com...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent