BDBM459484 US10752635, Example 35::US11492354, Example 35
SMILES COc1cccc(F)c1-c1nccc(n1)C(=O)Nc1cc(F)c2n(C)ncc2c1N1C[C@@H](O)C[C@H]1CN
InChI Key InChIKey=OHKSBENCBXMGAT-KBPBESRZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 459484
Affinity DataKi: 2.20nMAssay Description:In vitro inhibition of human carbonic anhydrase II (0.1 nM).More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Compound was evaluated for the inhibition of human Thymidylate SynthaseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against human carbonic anhydrase II using pH stat assayMore data for this Ligand-Target Pair