BDBM461336 US10774068, Example 41::US11427560, Example 41

SMILES CCOc1cc2ncc(C#N)c(Nc3ccc(OCc4cn5cccc(C)c5n4)c(Cl)c3)c2cc1NC(=O)CCCN(C)C

InChI Key InChIKey=IHQYGVLWVMMPRM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 461336   

TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM461336(US10774068, Example 41 | US11427560, Example 41)
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM461336(US10774068, Example 41 | US11427560, Example 41)
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase 4(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM461336(US10774068, Example 41 | US11427560, Example 41)
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSerine/threonine-protein kinase 3(Homo sapiens (Human))
The Scripps Research Institute

US Patent
LigandPNGBDBM461336(US10774068, Example 41 | US11427560, Example 41)
Affinity DataIC50: <100nMAssay Description:MST1 and MST2 biochemical LanthaScreen Eu Kinase Binding Assay was based on the binding and displacement of kinase tracer to the kinase of interest. ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent