BDBM464781 US10793563, Compound I-117::US10793563, Compound I-118::US10793563, Compound I-127

SMILES C[C@@H]1CN(C[C@@H](O1)c1cn[nH]c1)c1nccc(n1)-c1cnc2ccc(cn12)C(F)(F)F

InChI Key

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 464781   

TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM464781(US10793563, Compound I-117 | US10793563, Compound ...)
Affinity DataKi: <10nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM464781(US10793563, Compound I-117 | US10793563, Compound ...)
Affinity DataKi: <10nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargeteIF-2-alpha kinase GCN2(Homo sapiens (Human))
Merck Patent

US Patent
LigandPNGBDBM464781(US10793563, Compound I-117 | US10793563, Compound ...)
Affinity DataIC50: <10nMAssay Description:An assay buffer containing GCN2 kinase and (RS)7 was prepared. 4.7 μL of this stock solution was placed per well of a black, low volume, 384-wel...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent