BDBM465768 2-{3-[2-amino-6-(2- fluoropyridin-4-yl)-7H- pyrrolo[2,3-d]pyrimidin- 4-yl]-2-(hydroxy- methyl)phenyl)-6- cyclopropyl- 8-fluoroisoquinolin- 1(2H)-one::US10793575, Example 43

SMILES Nc1nc(-c2cccc(c2CO)-n2ccc3cc(cc(F)c3c2=O)C2CC2)c2cc([nH]c2n1)-c1ccnc(F)c1

InChI Key InChIKey=QYQGLCCCQMLCNW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 465768   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM465768(2-{3-[2-amino-6-(2- fluoropyridin-4-yl)-7H- pyrrol...)
Affinity DataIC50: <10nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trade mark) MSA (commercially available kit manufactured by Carna Biosciences, In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK [C481S](Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM465768(2-{3-[2-amino-6-(2- fluoropyridin-4-yl)-7H- pyrrol...)
Affinity DataIC50:  1.72nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trademark) MSA (commercially available kit manufactured by Carna Biosciences, Inc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Carna Biosciences

US Patent
LigandPNGBDBM465768(2-{3-[2-amino-6-(2- fluoropyridin-4-yl)-7H- pyrrol...)
Affinity DataIC50:  1.11nMAssay Description:The kinase activity was measured using QuickScout Screening Assist (trade mark) MSA (commercially available kit manufactured by Carna Biosciences, In...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent