BDBM466583 N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-yl}ethyl)-tetrahydro-2H-pyran-4-carboxamide::US10800755, Example 37::US11014905, Example 37

SMILES CNc1cccc(n1)C1CCN(CCNC(=O)C2CCOCC2)CC1

InChI Key InChIKey=MAOSODQBBXGYHQ-UHFFFAOYSA-N

Data  3 KI  3 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 466583   

TargetD(4) dopamine receptor(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466583(N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-y...)
Affinity DataKi:  73nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466583(N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-y...)
Affinity DataKi:  108nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466583(N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-y...)
Affinity DataKi: >1.00E+4nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(2) dopamine receptor(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466583(N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-y...)
Affinity DataIC50: >1.00E+4nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466583(N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-y...)
Affinity DataIC50:  108nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(4) dopamine receptor(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466583(N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-y...)
Affinity DataEC50:  52nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466583(N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-y...)
Affinity DataEC50:  343nMAssay Description:Aequorin, Gα16 proteins, and each receptor were transiently expressed in CHO-K1 cell (Chinese hamster ovary), and seeded to 384-well plate. The ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetD(4) dopamine receptor(Homo sapiens (Human))
Sumitomo Dainippon Pharma

US Patent
LigandPNGBDBM466583(N-(2-{4-[6-(Methylamino)pyridin-2-yl]piperidin-1-y...)
Affinity DataIC50:  73nMAssay Description:The binding affinity of the present compounds to human 5-HT1A receptor, human D4 receptor, and human D2 receptor was measured in a manner mentioned b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent