BDBM466713 US10800761, Example 32::US11731958, Example 32

SMILES CCN1C[C@H]2C[C@@H]1CN2c1ccc(F)cc1NC(=O)c1ccnc(n1)-c1c(F)cccc1OC

InChI Key InChIKey=VFYLBKWAGCOTCH-IAGOWNOFSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 466713   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM466713(US10800761, Example 32 | US11731958, Example 32)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMitogen-activated protein kinase kinase kinase kinase 1(Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM466713(US10800761, Example 32 | US11731958, Example 32)
Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent