BDBM468373 N,N′-(2-chloro-2′-cyanobiphenyl-3,3′-diyl)bis(l-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-2-carboxamide)::US10806785, Example 13

SMILES Cn1c2CCNCc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CNCCc3n2C)c1C#N

InChI Key InChIKey=LTGMFUHHXRWTBB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 468373   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM468373(N,N′-(2-chloro-2′-cyanobiphenyl-3,3...)
Affinity DataIC50: <0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM468373(N,N′-(2-chloro-2′-cyanobiphenyl-3,3...)
Affinity DataIC50:  0.550nMAssay Description:Binding assays were conducted in a low volume white 384-well polystyrene plate in a final volume of 20 μL. Compounds to be analyzed were first s...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent