BDBM468379 N-(2-chloro-2′-cyano-3′-(1,5-dimethyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-2-carboxamido)biphenyl-3-yl)-5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine-2-carboxamide::US10806785, Example 19
SMILES CN1CCc2c(C1)nc(C(=O)Nc1cccc(-c3cccc(NC(=O)c4nc5CCN(C)Cc5s4)c3Cl)c1C#N)n2C
InChI Key InChIKey=SKOHIIOUOCKZSL-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 468379
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: 0.550nMAssay Description:Binding assays were conducted in a low volume white 384-well polystyrene plate in a final volume of 20 μL. Compounds to be analyzed were first s...More data for this Ligand-Target Pair