BDBM468412 N-(2-chloro-3′-(5-(((R)-3-hydroxypyrrolidin-1-yl)methyl)-1-methyl-2-oxo-1,2-dihydropyridine-3-carboxamido)-2′-methylbiphenyl-3-yl)-5-((S)-2-hydroxypropyl)-1-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridine-2-carboxamide::US10806785, Example 51

SMILES C[C@H](O)CN1CCc2c(C1)nc(C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c3cc(CN4CC[C@@H](O)C4)cn(C)c3=O)c1C)n2C

InChI Key InChIKey=PSXAFGSDZBQEII-XUZZJYLKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 468412   

TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte

US Patent
LigandPNGBDBM468412(N-(2-chloro-3′-(5-(((R)-3-hydroxypyrrolidin-...)
Affinity DataIC50: <0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent