BDBM468420 US10806785, Example 64::trans-4-((2-(2,2'-dichloro-3'-(1- methyl-5-(tetrahydro-2H-pyran- 4-yl)-4,5,6,7-tetrahydro-1H- imidazo[4,5-c]pyridine-2- carboxamido)biphenyl-3- ylcarbamoyl)-1-methyl-6,7- dihydro-1H-imidazo[4,5- c]pyridin-5(4H)- yl)methyl)cyclohexane-1- carboxylic acid 1H NMR (600 MHz, DMSO-d6) $#948; 9.93 (s, 1H), 9.92 (s, 1H), 8.32 (d, J = 7.7 Hz, 1H), 8.31 (d, J = 7.7 Hz, 1H), 7.52 (t, J =
SMILES Cn1c2CCN(C[C@H]3CC[C@@H](CC3)C(O)=O)Cc2nc1C(=O)Nc1cccc(c1Cl)-c1cccc(NC(=O)c2nc3CN(CCc3n2C)C2CCOCC2)c1Cl
InChI Key InChIKey=KDCMCARJCJXNJM-SOAUALDESA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 468420
TargetProgrammed cell death 1 ligand 1 [19-238]/protein 1 [25-167](Homo sapiens (Human))
Incyte
US Patent
Incyte
US Patent
Affinity DataIC50: <0.100nMAssay Description:The assays were conducted in a standard black 384-well polystyrene plate with a final volume of 20 μL. Inhibitors were first serially diluted in...More data for this Ligand-Target Pair