BDBM471724 N4-(3,4-Ethylenedioxyphenyl)-5-fluoro-N2-(1-methyl-indazoline-5-yl)-2,4-pyrimidinediamine::US10828301, Compound R935193

SMILES Fc1cnc(Nc2ccc3[nH]ncc3c2)nc1Nc1ccc2OCCOc2c1

InChI Key InChIKey=XLRDFWRIOYMTEG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 471724   

TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Rigel Pharmceuticals

US Patent
LigandPNGBDBM471724(N4-(3,4-Ethylenedioxyphenyl)-5-fluoro-N2-(1-methyl...)
Affinity DataIC50:  75nMAssay Description:Several 2,4-pyrimidinediamine compounds were tested for the ability to inhibit Syk kinase catalyzed phosphorylation of a peptide substrate in a bioch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent