BDBM473894 5-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phenyl- sulfonamido)-2- hydroxybenzoic acid::US10858316, Compound LC-5-129

SMILES Cc1cc(Oc2ccc(cc2)S(=O)(=O)N(Cc2ccccc2)c2ccc(O)c(c2)C(O)=O)cc(C)c1Cl

InChI Key InChIKey=BJNRTUJJOHLFEL-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 473894   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM473894(5-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phe...)
Affinity DataKi:  1.40E+3nMAssay Description:Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetIsoform Bcl-X(L) of Bcl-2-like protein 1 (Bcl-xL)(Homo sapiens (Human))
University of Maryland, Baltimore

US Patent
LigandPNGBDBM473894(5-(N-benzyl-4-(4- chloro-3,5- dimethylphenoxy) phe...)
Affinity DataKi:  1.82E+3nMAssay Description:Molecular modeling and SILCS functional group affinity mapping (FragMaps) of the Mcl-1 binding site indicated that the carboxylic acid of designed mo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent