BDBM474101 Compound 8::US10858359, Example 8
SMILES CC(C)(C)[S@@](=O)N[C@@H]1COCC11CCN(CC1)c1cnc(Sc2cccc3NC(=O)C(F)(F)c23)c(N)n1
InChI Key InChIKey=QJBJZPKOHGGGHD-LUDUKKHASA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 474101
TargetTyrosine-protein phosphatase non-receptor type 11(Homo sapiens (Human))
Jacobio Pharmaceuticals
US Patent
Jacobio Pharmaceuticals
US Patent
Affinity DataIC50: 21.4nMAssay Description:IC50 values were estimated using 6,8-difluoro-4-methylumbelliferyl phosphate (DiFMUP) as a substrate, SHP2 samples (diluted to 0.5 nM in reaction buf...More data for this Ligand-Target Pair