BDBM474330 7-(4-fluoro-1H-pyrazol-1-yl)-2-((3-fluoropyridin- 2-yl)methyl)-8-(3-methylimidazo[l,2-a]pyridin- 6-yl)-[1,2,4]triazolo[1,5-c]pyrimidin-5-amine::US10858365, Compound 117

SMILES Cc1cnc2ccc(cn12)-c1c(nc(N)n2nc(Cc3ncccc3F)nc12)-n1cc(F)cn1

InChI Key InChIKey=XECCFMIBBHXKBJ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 474330   

TargetAdenosine receptor A2a(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474330(7-(4-fluoro-1H-pyrazol-1-yl)-2-((3-fluoropyridin- ...)
Affinity DataIC50:  0.200nMAssay Description:The compounds at different concentrations were incubate with hA1 membrane (from PerkinElmer) and [3H]-8-Cyclopentyl-1,3-dipropylxanthine (DPCPX) for ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A1(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474330(7-(4-fluoro-1H-pyrazol-1-yl)-2-((3-fluoropyridin- ...)
Affinity DataIC50:  9.70nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2a(Mus musculus)
TBA

US Patent
LigandPNGBDBM474330(7-(4-fluoro-1H-pyrazol-1-yl)-2-((3-fluoropyridin- ...)
Affinity DataIC50:  0.5nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetAdenosine receptor A2b(Homo sapiens (Human))
TBA

US Patent
LigandPNGBDBM474330(7-(4-fluoro-1H-pyrazol-1-yl)-2-((3-fluoropyridin- ...)
Affinity DataIC50:  16.4nMAssay Description:hADORA1/CHO (hA1 expressing) cells (Genscript) were plated at 1×104 cells/well into 384-well polystyrene plates one day before starting the experimen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent