BDBM475241 US10851082, NUCC-0176343::US10851082, NUCC-0200953

SMILES N#Cc1cnc(NCCc2ccncc2)nc1-n1cnc2ccccc12

InChI Key InChIKey=LWTZXHOFUFUYRH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 475241   

TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM475241(US10851082, NUCC-0176343 | US10851082, NUCC-020095...)
Affinity DataIC50:  6.5nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM475241(US10851082, NUCC-0176343 | US10851082, NUCC-020095...)
Affinity DataIC50:  5.50E+3nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM475241(US10851082, NUCC-0176343 | US10851082, NUCC-020095...)
Affinity DataIC50:  5.50E+3nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Northwestern University

US Patent
LigandPNGBDBM475241(US10851082, NUCC-0176343 | US10851082, NUCC-020095...)
Affinity DataIC50:  3.20nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent