BDBM475241 US10851082, NUCC-0176343::US10851082, NUCC-0200953
SMILES N#Cc1cnc(NCCc2ccncc2)nc1-n1cnc2ccccc12
InChI Key InChIKey=LWTZXHOFUFUYRH-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 475241
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 6.5nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 5.50E+3nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Northwestern University
US Patent
Northwestern University
US Patent
Affinity DataIC50: 3.20nMAssay Description:The synthesized compounds then were tested for inhibition of the kinase activity (IC50) of Mnk1 and/or Mnk2 using the ADP monitoring assay for kinase...More data for this Ligand-Target Pair