BDBM475621 US10851091, U.S. Pat. No. 8,242,104 No. 549 isomer 1
SMILES CC(C)n1ncnc1-c1cn2CCOc3cc(O[C@H](C4CC4)C(N)=O)ccc3-c2n1
InChI Key InChIKey=GFOJWGYPLGSKOJ-GOSISDBHSA-N
Data 2 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 475621
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 0.560nMAssay Description:The biochemical inhibition of four PI3K isoforms by the Formula I compounds of Table 1. In addition, two clinically tested PI3K compounds, taselisib ...More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Genentech
US Patent
Genentech
US Patent
Affinity DataKi: 9.41nMAssay Description:The biochemical inhibition of four PI3K isoforms by the Formula I compounds of Table 1. In addition, two clinically tested PI3K compounds, taselisib ...More data for this Ligand-Target Pair