BDBM475621 US10851091, U.S. Pat. No. 8,242,104 No. 549 isomer 1

SMILES CC(C)n1ncnc1-c1cn2CCOc3cc(O[C@H](C4CC4)C(N)=O)ccc3-c2n1

InChI Key InChIKey=GFOJWGYPLGSKOJ-GOSISDBHSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 475621   

LigandPNGBDBM475621(US10851091, U.S. Pat. No. 8,242,104 No. 549 isomer...)
Affinity DataKi:  0.560nMAssay Description:The biochemical inhibition of four PI3K isoforms by the Formula I compounds of Table 1. In addition, two clinically tested PI3K compounds, taselisib ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
LigandPNGBDBM475621(US10851091, U.S. Pat. No. 8,242,104 No. 549 isomer...)
Affinity DataKi:  9.41nMAssay Description:The biochemical inhibition of four PI3K isoforms by the Formula I compounds of Table 1. In addition, two clinically tested PI3K compounds, taselisib ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent