BDBM476694 (S)-6-(3-Chloro-8-(prop-1-yn-1-yl) dibenzo[b,d]thiophen-2-yl)-2-imino-3,6- dimethyltetrahydropyrimidin-4(1H)-one::US10870635, Example 71

SMILES CC#Cc1ccc2sc3cc(Cl)c(cc3c2c1)[C@]1(C)CC(=O)N(C)C(=N)N1

InChI Key InChIKey=AYIUXAXCNVTPTC-NRFANRHFSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 476694   

TargetCathepsin D(Homo sapiens (Human))
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476694((S)-6-(3-Chloro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...)
Affinity DataIC50:  3.90E+3nMAssay Description:Cathepsin D (Cat D) is a major intercellular member of the mammalian aspartic proteinase family and is thought to be in the normal degradation of int...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Allgenesis Biotherapeutics

US Patent
LigandPNGBDBM476694((S)-6-(3-Chloro-8-(prop-1-yn-1-yl) dibenzo[b,d]thi...)
Affinity DataIC50:  44nMAssay Description:A BACE1 activity assay kit from AnaSpec (Fremont, Calif.) was used to determine the potency of the selected BACE1 inhibitors by AnaSpec BACE1 fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent