BDBM476928 SARS-CoV-2 3CLpro Inhibitors 2a::SARS-CoV-2 3CLpro Inhibitors 2b
SMILES CC(C)C[C@H](NC(=O)OCC1CC2CCCC(C1)C2)C(=O)NC(CC1CCNC1=O)C=O
InChI Key InChIKey=YHWWOAJOMPQXED-KQMXEUTGSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 476928
Affinity DataIC50: 180nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
TargetReplicase polyprotein 1ab(Middle East respiratory syndrome-related coronavir...)
Wichita State University
Wichita State University
Affinity DataIC50: 52nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair
Affinity DataEC50: 35nMAssay Description:Compounds 2a and 3a were investigated for their antiviral activity against the replication of SARS-CoV-2. Briefly, confluent Vero E6 cells were inocu...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Cloning and Expression of the 3CL Protease of SARS-CoV-2 and FRET Enzyme Assays. The codon-optimized cDNA of full length of 3CLpro of SARS-CoV-2 (Gen...More data for this Ligand-Target Pair