BDBM477520 US10889555, Example 288::US11634395, Example 288

SMILES C[C@@H]([C@H](NS(=O)(=O)c1ccc(Cl)c2N(C)CCOc12)c1n[nH]c(=O)o1)c1c(F)ccc(C)c1C

InChI Key

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 477520   

TargetRibonucleoside-diphosphate reductase large subunit/subunit M2(Homo sapiens (Human))
Taiho Pharmaceutial

US Patent
LigandPNGBDBM477520(US10889555, Example 288 | US11634395, Example 288)
Affinity DataIC50:  60nMAssay Description:The inhibitory activity against the ribonucleotide reduction reaction (hereinafter referred to as RNR reaction) of the test compound was determined b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetMuscarinic acetylcholine receptor M1/M2(Homo sapiens (Human))
Taiho Pharmaceutical

US Patent
LigandPNGBDBM477520(US10889555, Example 288 | US11634395, Example 288)
Affinity DataIC50:  60nMAssay Description:First, test compounds were serially diluted with DMSO. Next, human M1 protein and human M2 protein were added to an aqueous albumin solution derived ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent