BDBM478956 N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(1'-propioloyl-1',2',5',6'-tetrahydro-[2,3'- bipyridin]-5-yl)acetamide::US10894786, Comp. No 58

SMILES O=C(Cc1ccc(nc1)C1=CCCN(C1)C(=O)C#C)Nc1cc([nH]n1)C1CC1

InChI Key InChIKey=AKMSYPYWPJSTGX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 478956   

TargetCyclin-dependent kinase 13(Homo sapiens (Human))
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478956(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(1'-propioloyl...)
Affinity DataIC50:  84nMAssay Description:LanthaScreen Eu Kinase Binding Assays are based on the binding and displacement of Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor scaffold...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 12(Homo sapiens)
Aurigene Discovery Technologies

US Patent
LigandPNGBDBM478956(N-(5-cyclopropyl-1H-pyrazol-3-yl)-2-(1'-propioloyl...)
Affinity DataIC50:  49nMAssay Description:The inhibitory activity of the test compounds was assessed by the LANCE TR-FRET assay, which detects the ATP-dependent phosphorylation of an ULight-4...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent