BDBM480562 3-(5-(3-Cyclopropyl-5,7-dimethyl-6-oxo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazin-1-yl)-3-(difluoromethyl)quinolin-2-yl)-1,2,4-thiadiazol-5(4H)-one::US10899769, Example 46

SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2nc(-c3nsc(=O)[nH]3)c(cc12)C(F)F

InChI Key

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 480562   

TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM480562(3-(5-(3-Cyclopropyl-5,7-dimethyl-6-oxo-5,6,7,8-tet...)
Affinity DataIC50:  341nMAssay Description:CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Board of Regents, The University of Texas System

US Patent
LigandPNGBDBM480562(3-(5-(3-Cyclopropyl-5,7-dimethyl-6-oxo-5,6,7,8-tet...)
Affinity DataIC50:  2nMAssay Description:BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent