BDBM480563 3-(8-(3-Cyclopropyl-5,7-dimethyl-6-oxo-5,6,7,8-tetrahydroimidazo[1,5-a]pyrazin-1-yl)isoquinolin-3-yl)-1,2,4-thiadiazol-5(4H)-one::US10899769, Example 47
SMILES CC1C(=O)N(C)Cc2c(nc(C3CC3)n12)-c1cccc2cc(ncc12)-c1nsc(=O)[nH]1
InChI Key
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 480563
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 1.46E+3nMAssay Description:CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 2nMAssay Description:BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair