BDBM480607 (R)-1-(3-(difluoromethyl)- 2-(1-methyl-1H-pyrazol-3- yl)quinolin-5-yl)-5,7- dimethyl-3-(tetrahydro-2H- pyran-4-yl)-7,8- dihydroimidazo[1,5-a] pyrazin-6(5H)-one::US10899769, Example 89a
SMILES C[C@@H]1C(=O)N(C)Cc2c(nc(C3CCOCC3)n12)-c1cccc2nc(-c3ccn(C)n3)c(cc12)C(F)F
InChI Key InChIKey=PMNZVZQYPSMXDO-OAHLLOKOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 480607
TargetCREB-binding protein [1081-1197](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 101nMAssay Description:CBP: 5 nM GST-CBP(1081-1197) and 20 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4 [49-170](Homo sapiens (Human))
Board of Regents, The University of Texas System
US Patent
Board of Regents, The University of Texas System
US Patent
Affinity DataIC50: 1nMAssay Description:BRD4: 2.5 nM of BRD4(49-170) and 10 nM biotin-H4(1-21) Ac-K5/8/12/16 (AnaSpec. 64989) were incubated with varying concentrations of CBP inhibitors in...More data for this Ligand-Target Pair