BDBM48076 3-amino-N-(2,3-difluorobenzyl)-4-methyl-6-(4-pyridylmethoxy)thieno[2,3-b]pyridine-2-carboxamide::3-amino-N-[(2,3-difluorophenyl)methyl]-4-methyl-6-(pyridin-4-ylmethoxy)-2-thieno[2,3-b]pyridinecarboxamide::3-amino-N-[(2,3-difluorophenyl)methyl]-4-methyl-6-(pyridin-4-ylmethoxy)thieno[2,3-b]pyridine-2-carboxamide::3-azanyl-N-[[2,3-bis(fluoranyl)phenyl]methyl]-4-methyl-6-(pyridin-4-ylmethoxy)thieno[2,3-b]pyridine-2-carboxamide::ML173::VU0359508::cid_45142486
SMILES Cc1cc(OCc2ccncc2)nc2sc(C(=O)NCc3cccc(F)c3F)c(N)c12
InChI Key InChIKey=WISIHNWJSXFHCG-UHFFFAOYSA-N
Data 7 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 48076
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 1.61E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 1.67E+3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 95.3nMAssay Description:Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University Grant Title: Discovery of a Highly Selective in vitro and in vivo...More data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 2.40E+3nMAssay Description:Positive allosteric modulation of rat M4 AchRMore data for this Ligand-Target Pair
TargetMuscarinic acetylcholine receptor M4(RAT)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters
Curated by PubChem BioAssay
Affinity DataEC50: 900nMAssay Description:Positive allosteric modulation of rat muscarinic M4 receptor assessed as acetylcholine responseMore data for this Ligand-Target Pair
Affinity DataEC50: 95nMAssay Description:Positive allosteric modulation of human M4 AchRMore data for this Ligand-Target Pair
Affinity DataEC50: 500nMAssay Description:Positive allosteric modulation of human muscarinic M4 receptor expressed in CHO-K1 cells assessed as leftward shift in acetylcholine response treated...More data for this Ligand-Target Pair