BDBM481254 3-(3-ethyl-4-oxo- spiro[6,8-dihydro-5H- pyrazolo[4,3-c]azepine- 7,4'-tetrahydropyran]-1- yl)propyl 3,4- difluorobenzoate::US10906915, Ex. 44

SMILES CCc1nn(CCCOC(=O)c2ccc(F)c(F)c2)c2CC3(CCOCC3)CNC(=O)c12

InChI Key InChIKey=SJBSBUSUDKQRMT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481254   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM481254(3-(3-ethyl-4-oxo- spiro[6,8-dihydro-5H- pyrazolo[4...)
Affinity DataIC50: <100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent