BDBM481269 3-(3-ethyl-4-oxo- spiro[6,8-dihydro-5H- pyrazolo[4,3-c]azepine- 7,4'-tetrahydropyran]-1- yl)propyl 3-methoxy-4- methyl-benzoate::US10906915, Ex. 59

SMILES CCc1nn(CCCOC(=O)c2ccc(C)c(OC)c2)c2CC3(CCOCC3)CNC(=O)c12

InChI Key InChIKey=RAFLQPKDNUEQGT-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 481269   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Leo Pharma

US Patent
LigandPNGBDBM481269(3-(3-ethyl-4-oxo- spiro[6,8-dihydro-5H- pyrazolo[4...)
Affinity DataIC50: <100nMAssay Description:The human PDE4D catalytic domain (UniProt no. Q08499 [5380-L740]) was incubated with a mixture of non-labelled cAMP (cyclic adenosine monophosphate) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent