BDBM48320 4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide;hydrochloride::4-azanyl-5-chloranyl-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide;hydrochloride::METOCLOPRAMIDE::METOCLOPRAMIDE HYDROCHLORIDE::MLS000069667::Metochloropramide::SMR000058471::US11147820, Compound Metoclopramide::US11717500, Compound Metoclopramide::US9132134, Metoclopramide::cid_23659
SMILES CCN(CC)CCNC(=O)c1cc(Cl)c(N)cc1OC
InChI Key InChIKey=TTWJBBZEZQICBI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 93 hits for monomerid = 48320
Affinity DataEC50: 5.70nMAssay Description:5-hydroxytryptamine 4 receptor agonist activity, concentration which gave 50% increase in the response to electrically-stimulated myenteric plexus an...More data for this Ligand-Target Pair
Affinity DataKi: 16nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
Affinity DataKi: 27nMAssay Description:Displacement of [125I]iodosulpiride from human Dopamine receptor D3 expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 61.3nMAssay Description:Concentration of compound required to inhibit the binding of radioligand [3H](R)-7-OH-DPAT to Dopamine receptor D3 in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 64nMAssay Description:The pharmacological profile of metopimazine, metopimazine acid (MPZA), domperidone, and metoclopramide were assessed by radioligand binding and by a ...More data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:It is well-known that drug compounds that have an affinity for the striatal dopamine D2 may give rise to adverse side effects, such as short-term ext...More data for this Ligand-Target Pair
Affinity DataKi: 80nMAssay Description:Compound was evaluated for the binding affinity at Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPIMore data for this Ligand-Target Pair
Affinity DataKi: 104nMAssay Description:Compound was evaluated for binding affinity towards DA D-2 receptor using radioligand [3H]SPIMore data for this Ligand-Target Pair
Affinity DataKi: 113nMAssay Description:Binding affinity to dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 158nMAssay Description:Tested for its binding affinity by measuring its ability to displace [3H]granisetron from 5-hydroxytryptamine 3 receptor in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 200nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor using [3H]GR-65630 as radioligand in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 210nMAssay Description:Inhibition of [3H]GR-65630 binding to rat cortical membrane serotonin 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKd: 224nMAssay Description:Binding affinity towards 5-hydroxytryptamine 3 receptor was determined by using [3H]-ICS 205-930 as radioligand in mouse N1E 115 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 228nMAssay Description:Concentration required to inhibit the binding of radioligand [3H]GR-65630 to serotonin 5-hydroxytryptamine-3 receptor (5-HT 3 receptor)in rat brain c...More data for this Ligand-Target Pair
Affinity DataKi: 229nMAssay Description:Binding affinity to 5-hydroxytryptamine 3 receptor using [3H]quipazine as radioligand in rat cortexMore data for this Ligand-Target Pair
Affinity DataKi: 240nMAssay Description:Inhibition of [3H]GR-65630 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:The functional antagonist assay was performed as described in Payne, S. L et al. (2002) J. Neurochem., 82: 1106-1117, hereby incorporated by referenc...More data for this Ligand-Target Pair
Affinity DataKi: 285nMAssay Description:Binding affinity against Dopamine receptor D2 using [3H]spiperone as radioligand in rat striatumMore data for this Ligand-Target Pair
Affinity DataKi: 303nMAssay Description:Affinity towards Dopamine receptor D2 in rat striatum using [3H]spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 348nMAssay Description:Compound was evaluated for its binding affinity for 5-hydroxytryptamine 3 receptor by measuring displacement [3H]GR-65630 in rat cerebral cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of recombinant MPO (unknown origin) assessed as reduction in taurine chloramine production preincubated with enzyme and taurine followed b...More data for this Ligand-Target Pair
Affinity DataKi: 443nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 as radioligand in rat posterior cortexMore data for this Ligand-Target Pair
Affinity DataKi: 443nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor using [3H]BRL-43694 in rat posterior cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 444nMAssay Description:Concentration of compound required to inhibit the binding of radioligand [3H]spiperone to Dopamine receptor D2 in rat brain synaptic membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Binding affinity against dopamine D2 receptor in rat brain synaptic membrane using [3H]-spiperone as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 480nMAssay Description:Inhibition of [3H]- spiperone binding to rat brain Dopamine receptor D2More data for this Ligand-Target Pair
Affinity DataKi: 490nMAssay Description:Binding affinity at 5-hydroxytryptamine 3 receptor in rat entorhinal cortex by [3H]BRL-43694 displacement.More data for this Ligand-Target Pair
Affinity DataKi: 501nMAssay Description:pKi value for inhibition of [3H]LY-278584 binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 502nMAssay Description:Inhibitory activity against 5-hydroxytryptamine 3 receptor in rat cortical membranes using [3H]- 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-a...More data for this Ligand-Target Pair
Affinity DataKi: 546nMAssay Description:Inhibition of [3H]GR-113808 binding to guinea pig striatum 5-hydroxytryptamine 4 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 565nMAssay Description:In vitro antagonistic activity against Dopamine receptor D2 was evaluated for the inhibition of [3H]spiperone bindingMore data for this Ligand-Target Pair
Affinity DataIC50: 630nMAssay Description:Inhibitory activity against dopamine receptor D2 by 3H ligand binding experiments.More data for this Ligand-Target Pair
Affinity DataEC50: 794nMAssay Description:Tested for its agonist potency against the 5-hydroxytryptamine 4 receptor located in the rat esophageal tunica muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataEC50: 794nMAssay Description:Agonist activity against 5-HT4 receptor in rat esophageal muscularis mucosaeMore data for this Ligand-Target Pair
Affinity DataIC50: 820nMAssay Description:Inhibitory concentration required for displacing radioligand [3H]SPI from DA D-2 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 880nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 receptor in rat cortical membrane using [3H]GR-65630 as radioligandMore data for this Ligand-Target Pair