BDBM484045 (S)-1-(3-(2- hydroxyethylsulfonyl) phenoxy)-3-(R)-8- (quinolin-3-ylsulfonyl)- 1-oxa-8- azaspiro[4.5]decan-3- ylamino)propan-2-ol::US10927123, Compound 88

SMILES OCCS(=O)(=O)c1cccc(OC[C@@H](O)CN[C@H]2COC3(C2)CCN(CC3)S(=O)(=O)c2cnc3ccccc3c2)c1

InChI Key InChIKey=VZYAQGTUMRXLOW-PKTZIBPZSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484045   

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484045((S)-1-(3-(2- hydroxyethylsulfonyl) phenoxy)-3-(R)-...)
Affinity DataIC50:  2.51E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent