BDBM484076 3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)-2- hydroxypropylamino)-1- oxa-8-azaspiro[4.5]decan- 8-ylsulfonyl)quinolin- 4(1H)-one::US10927123, Compound 326

SMILES O[C@@H](CN[C@H]1COC2(C1)CCN(CC2)S(=O)(=O)c1c[nH]c2ccccc2c1=O)COc1cccc(c1)S(=O)(=O)C1CC1

InChI Key

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484076   

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484076(3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)...)
Affinity DataIC50:  1.73E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent