BDBM484077 3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)-2- hydroxypropylamino)-1- oxa-8-azaspiro[4.5]decan- 8-ylsulfonyl)-8- methylquinolin-4-ol::US10927123, Compound 327

SMILES Cc1cccc2c(O)c(cnc12)S(=O)(=O)N1CCC2(C[C@H](CO2)NC[C@H](O)COc2cccc(c2)S(=O)(=O)C2CC2)CC1

InChI Key InChIKey=XYIBFCSTTYQYHQ-YADHBBJMSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 484077   

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
Arena Pharmaceuticals

US Patent
LigandPNGBDBM484077(3-((R)-3-((S)-3-(3- (cyclopropylsulfonyl) phenoxy)...)
Affinity DataIC50:  2.89E+4nMAssay Description:Compounds were dissolved and serially diluted (5-fold) in DMSO to generate a 10-point dose response stock. The stock was then diluted 100-fold in ass...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent