BDBM484208 Inhibitor 16 of SARS-CoV-2 Mpro

SMILES Cn1cc(-c2cc(-c3cc(Cl)cc(OCC4CC4)c3)c(=O)n(c2)-c2cccnc2)c(=O)[nH]c1=O

InChI Key InChIKey=WQPXNFAUKKEFHC-UHFFFAOYSA-N

Data  1 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 484208   

TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM484208(Inhibitor 16 of SARS-CoV-2 Mpro)
Affinity DataIC50:  61nMAssay Description:Purified protein is diluted in reaction buffer to 100 nM in an opaque 96-well plate. The protein is incubated with or without compound in DMSO at dif...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM484208(Inhibitor 16 of SARS-CoV-2 Mpro)
Affinity DataEC50:  1.20E+3nMAssay Description:These assays are from various references.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Yale University

LigandPNGBDBM484208(Inhibitor 16 of SARS-CoV-2 Mpro)
Affinity DataEC50:  530nMAssay Description:These include a rapid screening replicon assay using baby hamster kidney (BHK) cells with noninfectious SARS-CoV-2, in which the spike protein in the...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed