BDBM485053 US10934303, Cmpd No. 18b::US10934303, Example 21::US10934303, Example 25::US11285226, Compound 18b

SMILES CC(C)N1CCN(CC1)c1ccc(cc1)C(=C(\CCCO)c1ccccc1)\c1ccc(C)cc1

InChI Key InChIKey=NXHXHKXWVITXTN-KTMFPKCZSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 485053   

TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50:  17nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50:  861nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50:  26nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50:  1.02E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50:  17nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50:  861nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485053(US10934303, Cmpd No. 18b | US10934303, Example 21 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent