BDBM485060 US10934303, Cmpd No. 18k::US10934303, Example 30::US11285226, Compound 18k

SMILES CC(C)N1CCN(CC1)c1ccc(cc1)C(=C(\CCCO)c1ccccc1)\c1cccc(O)c1

InChI Key InChIKey=MVDJTCFLEZIJEJ-QVIHXGFCSA-N

Data  15 IC50

PDB links: 1 PDB ID matches this monomer.

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Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 485060   

TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50:  35nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50:  1.94E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50:  1.94E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50:  35nMAssay Description:Binding affinity to ERRgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to ERRalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to ERRbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50:  1.94E+3nMAssay Description:Binding affinity to ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50:  2.46E+4nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG currentMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50:  20nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50:  35nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485060(US10934303, Cmpd No. 18k | US10934303, Example 30 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
In DepthDetails US Patent