BDBM485065 US10934303, Cmpd No. 22g::US10934303, Example 58::US10934303, Example 62::US11285226, Compound 22k

SMILES CC(C)N1CCC(CC1)c1ccc(cc1)C(=C(\CCCO)c1ccccc1)\c1ccc(O)cc1

InChI Key InChIKey=WFBBMXRSHREWDN-NVQSTNCTSA-N

Data  22 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 485065   

TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  95nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  1.38E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  6.77E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  4.37E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  49nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  4.82E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  1.38E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  95nMAssay Description:Binding affinity to ERRgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to ERRalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  6.77E+3nMAssay Description:Binding affinity to ERRbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  4.37E+3nMAssay Description:Binding affinity to ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  131nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  95nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  6.77E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  4.37E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  49nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50:  4.82E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485065(US10934303, Cmpd No. 22g | US10934303, Example 58 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent