BDBM485066 US10934303, Cmpd No. 22i::US10934303, Example 60::US11285226, Compound 22i

SMILES OCCC\C(=C(/c1ccc(O)cc1)c1ccc(cc1)C1CCN(CC1)C1CC1)c1ccccc1

InChI Key InChIKey=QLPDYHPRQYYVTE-NVQSTNCTSA-N

Data  14 IC50

PDB links: 1 PDB ID matches this monomer.

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Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 485066   

TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  56nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  1.67E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  2.09E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  56nMAssay Description:Binding affinity to ERRgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to ERRalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  2.09E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  2.09E+3nMAssay Description:Binding affinity to ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  44nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  56nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  1.67E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485066(US10934303, Cmpd No. 22i | US10934303, Example 60 ...)
Affinity DataIC50:  1.67E+3nMAssay Description:Binding affinity to ERRbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed