BDBM485071 US10934303, Cmpd No. 22t::US10934303, Example 71::US11285226, Compound 22t

SMILES OCCC\C(=C(/c1ccc(O)cc1)c1ccc(cc1)C1CCN(C1)C1CC1)c1ccccc1

InChI Key InChIKey=ODOIDIKDWZDOBW-QVIHXGFCSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 485071   

TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  96nMAssay Description:ERRγ: The arylethene derivative of the present invention was sequentially added to a 384 well plate from a concentration of 10 μM to a fina...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  3.56E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  5.94E+3nMAssay Description:ERRα/ERRβ/ERα : In an ERR beta binding assay, GST-bound ERR alpha LBD was used so that a final concentration was 10 nM and a fluoresce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  96nMAssay Description:Binding affinity to ERRgamma (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to ERRalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  5.94E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEstrogen receptor(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  5.94E+3nMAssay Description:Binding affinity to ERalpha (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

Curated by ChEMBL
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  4.30E+3nMAssay Description:Inhibition of human ERG by fluorescence polarization assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  99nMAssay Description:Inverse agonist activity at ERRgamma (unknown origin) by luciferase reporter gene assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen-related receptor gamma(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  96nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR1(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50: >1.00E+4nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  3.56E+3nMAssay Description:In an ERR alpha binding assay, GST-bound ERR alpha LBD was used, and all experiments other than that was the same as the ERR gamma binding assay.In a...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid hormone receptor ERR2(Homo sapiens (Human))
Daegu-Gyeongbuk Medical Innovation Foundation

US Patent
LigandPNGBDBM485071(US10934303, Cmpd No. 22t | US10934303, Example 71 ...)
Affinity DataIC50:  3.56E+3nMAssay Description:Binding affinity to ERRbeta (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed