BDBM488029 (4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- yl)pyrimidin-2- yl)amino)phenyl) (4-(4- fluorophenyl)piperazin- 1-yl)methanone::US10954216, Example 3

SMILES CCn1cc(c(n1)-c1cccnc1)-c1ccnc(Nc2ccc(cc2)C(=O)N2CCN(CC2)c2ccc(F)cc2)n1

InChI Key InChIKey=ZZDRWUDRBDVWLW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 488029   

TargetActivin receptor type-1(Human)
Riken

US Patent
LigandPNGBDBM488029((4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- y...)
Affinity DataIC50:  24.2nMAssay Description:TABLE 5: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 is as follows. In a buffer sol...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetActivin receptor type-1 [R206H](Human)
Riken

US Patent
LigandPNGBDBM488029((4-((4-(1-Ethyl-3- (pyridin-3-yl)-1H- pyrazol-4- y...)
Affinity DataIC50:  13.5nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent