BDBM488030 2-Methyl-N-(4-(1- (oxetan-3-yl)-3- (pyridin-3-yl)-1H- pyrazol-4- yl)pyrimidin-2-yl)- 1,2,3,4- tetrahydroisoquinolin- 6-amine::US10954216, Example 8

SMILES CN1CCc2cc(Nc3nccc(n3)-c3cn(nc3-c3cccnc3)C3COC3)ccc2C1

InChI Key InChIKey=CKMYFSYZOMWJLX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 488030   

TargetActivin receptor type-1 [R206H](Homo sapiens (Human))
Riken

US Patent
LigandPNGBDBM488030(2-Methyl-N-(4-(1- (oxetan-3-yl)-3- (pyridin-3-yl)-...)
Affinity DataIC50:  18.7nMAssay Description:R206H: An overview of evaluation of an inhibitory effect of a compound of the present invention with respect to ALK2 (R206H) is as follows.In a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent